Membrane Estrogen Receptors Acting Through Metabotropic Glutamate Receptors: An Emerging Mechanism of Estrogen Action in Brain
نویسندگان
چکیده
منابع مشابه
Estrogen receptors stimulate brain region specific metabotropic glutamate receptors to rapidly initiate signal transduction pathways.
Estradiol and other steroid hormones modulate the nervous system and behavior on both acute and long-term time scales. Though estradiol was originally characterized as a regulator of gene expression through the action of nuclear estrogen receptors (ERs) that directly bind DNA, research over the past thirty years has firmly established that estradiol can bind to extra-nuclear ERs associated with...
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ژورنال
عنوان ژورنال: Molecular Neurobiology
سال: 2008
ISSN: 0893-7648,1559-1182
DOI: 10.1007/s12035-008-8034-z